anti sirtuin 1 Search Results


sirt1  (Rockland Immunochemicals)
93
Rockland Immunochemicals sirt1
Sirt1, supplied by Rockland Immunochemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+sirtuin+1/SIRT1+Antibody/ppr0485182-53-37-45
Average 93 stars, based on 1 article reviews
sirt1 - by Bioz Stars, 2026-10
93/100 stars
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sirt1 polyclonal antibody  (Boster Bio)
91
Boster Bio sirt1 polyclonal antibody
Proposed mechanism of YJZYD in regulating the primordial follicle initiation rate and microenvironment. YJZYD inhibits LTCONS-00011173 expression, leading to enhanced Smad1 phosphorylation. This activates two downstream pathways: (1) <t>AMPK/SIRT1/PGC-1α</t> pathway promoting mitochondrial biogenesis and antioxidant function (increased SOD, ATP; decreased MDA). (2) Modulation of follicular regulatory factors (decreased PTEN, MST; increased AMH, GDF9) to balance primordial follicle initiation and growth. Solid arrows indicate direct activation; dashed arrows denote indirect regulation or material transport
Sirt1 Polyclonal Antibody, supplied by Boster Bio, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+sirtuin+1/Anti-SIRT1+Antibody+Picoband/pmc12870358-137-66-71
Average 91 stars, based on 1 article reviews
sirt1 polyclonal antibody - by Bioz Stars, 2026-10
91/100 stars
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sirt1  (Boster Bio)
94
Boster Bio sirt1
<t>SIRT1/NRF2/GPX4</t> pathway is involved in hippocampal ferroptosis in aged mice. (A) WB images and quantification analysis of <t>SIRT1,</t> NRF2 and GPX4 in the hippocampus of aged mice. (B) WB images and quantification analysis of SLC7A11, TFR1, IRP2 and ferritin in the hippocampus of aged mice ( n = 3 per group). (C) qRT‐PCR expression of SIRT1, NRF2, GPX4, SLC7A11, TFR1, IRP2 and ferritin mRNA in the hippocampus of aged mice ( n = 3 per group). Values are presented as mean ± SEM. ** p < 0.01 compared with the C group; # p < 0.05 and ## p < 0.01 compared with the M group; + p < 0.05 and ++ p < 0.01 and compared with the EX group.
Sirt1, supplied by Boster Bio, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+sirtuin+1/Anti-SIRT1+Antibody/pmc12796855-112-11-14
Average 94 stars, based on 1 article reviews
sirt1 - by Bioz Stars, 2026-10
94/100 stars
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rat tgf β  (Boster Bio)
90
Boster Bio rat tgf β
<t>SIRT1/NRF2/GPX4</t> pathway is involved in hippocampal ferroptosis in aged mice. (A) WB images and quantification analysis of <t>SIRT1,</t> NRF2 and GPX4 in the hippocampus of aged mice. (B) WB images and quantification analysis of SLC7A11, TFR1, IRP2 and ferritin in the hippocampus of aged mice ( n = 3 per group). (C) qRT‐PCR expression of SIRT1, NRF2, GPX4, SLC7A11, TFR1, IRP2 and ferritin mRNA in the hippocampus of aged mice ( n = 3 per group). Values are presented as mean ± SEM. ** p < 0.01 compared with the C group; # p < 0.05 and ## p < 0.01 compared with the M group; + p < 0.05 and ++ p < 0.01 and compared with the EX group.
Rat Tgf β, supplied by Boster Bio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+sirtuin+1/Anti-TGF+beta+1%2FTGFB1+Antibody/pmc04723553-82-4-9
Average 90 stars, based on 1 article reviews
rat tgf β - by Bioz Stars, 2026-10
90/100 stars
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anti-sirtuin 1 antibody  (GeneTex)
90
GeneTex anti-sirtuin 1 antibody
<t>SIRT1/NRF2/GPX4</t> pathway is involved in hippocampal ferroptosis in aged mice. (A) WB images and quantification analysis of <t>SIRT1,</t> NRF2 and GPX4 in the hippocampus of aged mice. (B) WB images and quantification analysis of SLC7A11, TFR1, IRP2 and ferritin in the hippocampus of aged mice ( n = 3 per group). (C) qRT‐PCR expression of SIRT1, NRF2, GPX4, SLC7A11, TFR1, IRP2 and ferritin mRNA in the hippocampus of aged mice ( n = 3 per group). Values are presented as mean ± SEM. ** p < 0.01 compared with the C group; # p < 0.05 and ## p < 0.01 compared with the M group; + p < 0.05 and ++ p < 0.01 and compared with the EX group.
Anti Sirtuin 1 Antibody, supplied by GeneTex, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+sirtuin+1/anti+sirtuin+1+antibody/pm31657248-164-7-16
Average 90 stars, based on 1 article reviews
anti-sirtuin 1 antibody - by Bioz Stars, 2026-10
90/100 stars
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sirtuin 1/sirt1 antibody  (Bio-Techne corporation)
93
Bio-Techne corporation sirtuin 1/sirt1 antibody
<t>SIRT1/NRF2/GPX4</t> pathway is involved in hippocampal ferroptosis in aged mice. (A) WB images and quantification analysis of <t>SIRT1,</t> NRF2 and GPX4 in the hippocampus of aged mice. (B) WB images and quantification analysis of SLC7A11, TFR1, IRP2 and ferritin in the hippocampus of aged mice ( n = 3 per group). (C) qRT‐PCR expression of SIRT1, NRF2, GPX4, SLC7A11, TFR1, IRP2 and ferritin mRNA in the hippocampus of aged mice ( n = 3 per group). Values are presented as mean ± SEM. ** p < 0.01 compared with the C group; # p < 0.05 and ## p < 0.01 compared with the M group; + p < 0.05 and ++ p < 0.01 and compared with the EX group.
Sirtuin 1/Sirt1 Antibody, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+sirtuin+1/Sirtuin+1%2FSIRT1+Antibody/custom%40nbp2-27205%4037495029
Average 93 stars, based on 1 article reviews
sirtuin 1/sirt1 antibody - by Bioz Stars, 2026-10
93/100 stars
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sirt1 sirtuin 1 polyclonal antibody  (Bioss)
94
Bioss sirt1 sirtuin 1 polyclonal antibody
<t>SIRT1/NRF2/GPX4</t> pathway is involved in hippocampal ferroptosis in aged mice. (A) WB images and quantification analysis of <t>SIRT1,</t> NRF2 and GPX4 in the hippocampus of aged mice. (B) WB images and quantification analysis of SLC7A11, TFR1, IRP2 and ferritin in the hippocampus of aged mice ( n = 3 per group). (C) qRT‐PCR expression of SIRT1, NRF2, GPX4, SLC7A11, TFR1, IRP2 and ferritin mRNA in the hippocampus of aged mice ( n = 3 per group). Values are presented as mean ± SEM. ** p < 0.01 compared with the C group; # p < 0.05 and ## p < 0.01 compared with the M group; + p < 0.05 and ++ p < 0.01 and compared with the EX group.
Sirt1 Sirtuin 1 Polyclonal Antibody, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+sirtuin+1/SIRT1+sirtuin+1+Polyclonal+Antibody/custom%40bs-2257r%4034843934
Average 94 stars, based on 1 article reviews
sirt1 sirtuin 1 polyclonal antibody - by Bioz Stars, 2026-10
94/100 stars
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sirtuin 1 sirt1  (Signalway Antibody)
86
Signalway Antibody sirtuin 1 sirt1
<t>SIRT1/NRF2/GPX4</t> pathway is involved in hippocampal ferroptosis in aged mice. (A) WB images and quantification analysis of <t>SIRT1,</t> NRF2 and GPX4 in the hippocampus of aged mice. (B) WB images and quantification analysis of SLC7A11, TFR1, IRP2 and ferritin in the hippocampus of aged mice ( n = 3 per group). (C) qRT‐PCR expression of SIRT1, NRF2, GPX4, SLC7A11, TFR1, IRP2 and ferritin mRNA in the hippocampus of aged mice ( n = 3 per group). Values are presented as mean ± SEM. ** p < 0.01 compared with the C group; # p < 0.05 and ## p < 0.01 compared with the M group; + p < 0.05 and ++ p < 0.01 and compared with the EX group.
Sirtuin 1 Sirt1, supplied by Signalway Antibody, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+sirtuin+1/1+anti+sirt1+sirtuin/pm41275826-103-44-47
Average 86 stars, based on 1 article reviews
sirtuin 1 sirt1 - by Bioz Stars, 2026-10
86/100 stars
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anti-sirtuin 1 antibody  (St Johns Laboratory)
N/A
Goat polyclonal to Sirtuin 1. Conjugation note: Unconjugated Application note: ELISA, WB, IHC Reactivity note: Human
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goat anti-sirtuin 1 / sirt1 (aa577-590)  (everest biotech)
N/A
This antibody is expected to recognize both reported isoforms (NP_036370.2; NP_001135970.1).
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Image Search Results


Proposed mechanism of YJZYD in regulating the primordial follicle initiation rate and microenvironment. YJZYD inhibits LTCONS-00011173 expression, leading to enhanced Smad1 phosphorylation. This activates two downstream pathways: (1) AMPK/SIRT1/PGC-1α pathway promoting mitochondrial biogenesis and antioxidant function (increased SOD, ATP; decreased MDA). (2) Modulation of follicular regulatory factors (decreased PTEN, MST; increased AMH, GDF9) to balance primordial follicle initiation and growth. Solid arrows indicate direct activation; dashed arrows denote indirect regulation or material transport

Journal: Journal of Ovarian Research

Article Title: Yangjingzhongyu Decoction regulates primordial follicle initiation via LncRNA-Smad1/AMPK dual pathways in diminished ovarian reserve

doi: 10.1186/s13048-025-01955-1

Figure Lengend Snippet: Proposed mechanism of YJZYD in regulating the primordial follicle initiation rate and microenvironment. YJZYD inhibits LTCONS-00011173 expression, leading to enhanced Smad1 phosphorylation. This activates two downstream pathways: (1) AMPK/SIRT1/PGC-1α pathway promoting mitochondrial biogenesis and antioxidant function (increased SOD, ATP; decreased MDA). (2) Modulation of follicular regulatory factors (decreased PTEN, MST; increased AMH, GDF9) to balance primordial follicle initiation and growth. Solid arrows indicate direct activation; dashed arrows denote indirect regulation or material transport

Article Snippet: Protein bands were analyzed using an electrochemilluminescence (ECL) chemil uminescence kit and the bands intensity was quantified using the GIS1000 Imaging system with the following primary antibodies: Smad1 polyclonal antibody (10429-1-AP, 1:5000, Proteintech, USA), Anti-Mullerian hormone (AMH) polyclonal antibody (14461-1-AP, 1:5000, Proteintech, USA), phosphate and tensin homolog (PTEN) polyclonal antibody (10047-1-AP, 1:5000, Proteintech, USA), AMP-activated protein kinase (AMPK) polyclonal antibody (10929-2-AP, 1:5000, proteintech, Wuhan, China) and SIRT1 polyclonal antibody (A00018-1, 1:1000, Boster, Wuhan, China).

Techniques: Expressing, Phospho-proteomics, Activation Assay

Molecular docking of YJZYD monomers. A Heatmap of binding energies. B - H . 2D interaction diagrams: ( B ) AMPK-Curcumin, ( C ) AMPK-m-Cresol, ( D ) SIRT1-Apigenin, ( E ) SIRT1-Curcumin, ( F ) SIRT1-m-Cresol, ( G ) MAP3K7-Apigenin, ( H ) MAP3K7-m-Cresol. I Docking energy legend. Docking scores: Strong binding: < -8 kcal/mol; Moderate: < -5 kcal/mol

Journal: Journal of Ovarian Research

Article Title: Yangjingzhongyu Decoction regulates primordial follicle initiation via LncRNA-Smad1/AMPK dual pathways in diminished ovarian reserve

doi: 10.1186/s13048-025-01955-1

Figure Lengend Snippet: Molecular docking of YJZYD monomers. A Heatmap of binding energies. B - H . 2D interaction diagrams: ( B ) AMPK-Curcumin, ( C ) AMPK-m-Cresol, ( D ) SIRT1-Apigenin, ( E ) SIRT1-Curcumin, ( F ) SIRT1-m-Cresol, ( G ) MAP3K7-Apigenin, ( H ) MAP3K7-m-Cresol. I Docking energy legend. Docking scores: Strong binding: < -8 kcal/mol; Moderate: < -5 kcal/mol

Article Snippet: Protein bands were analyzed using an electrochemilluminescence (ECL) chemil uminescence kit and the bands intensity was quantified using the GIS1000 Imaging system with the following primary antibodies: Smad1 polyclonal antibody (10429-1-AP, 1:5000, Proteintech, USA), Anti-Mullerian hormone (AMH) polyclonal antibody (14461-1-AP, 1:5000, Proteintech, USA), phosphate and tensin homolog (PTEN) polyclonal antibody (10047-1-AP, 1:5000, Proteintech, USA), AMP-activated protein kinase (AMPK) polyclonal antibody (10929-2-AP, 1:5000, proteintech, Wuhan, China) and SIRT1 polyclonal antibody (A00018-1, 1:1000, Boster, Wuhan, China).

Techniques: Binding Assay

YJZYD enhances mitochondrial function and antioxidant capacity. A AMPK/SIRT1/PGC-1α mRNA expression. B - C Corresponding protein expression and immunoblots. D - F SOD, MDA, and ATP levels. Statistical analysis ( n = 3): Model vs. Control: * p < 0.05; YJZYD vs. Model: # p < 0.05. MRNA compared to β-actin, protein compared to GAPDH

Journal: Journal of Ovarian Research

Article Title: Yangjingzhongyu Decoction regulates primordial follicle initiation via LncRNA-Smad1/AMPK dual pathways in diminished ovarian reserve

doi: 10.1186/s13048-025-01955-1

Figure Lengend Snippet: YJZYD enhances mitochondrial function and antioxidant capacity. A AMPK/SIRT1/PGC-1α mRNA expression. B - C Corresponding protein expression and immunoblots. D - F SOD, MDA, and ATP levels. Statistical analysis ( n = 3): Model vs. Control: * p < 0.05; YJZYD vs. Model: # p < 0.05. MRNA compared to β-actin, protein compared to GAPDH

Article Snippet: Protein bands were analyzed using an electrochemilluminescence (ECL) chemil uminescence kit and the bands intensity was quantified using the GIS1000 Imaging system with the following primary antibodies: Smad1 polyclonal antibody (10429-1-AP, 1:5000, Proteintech, USA), Anti-Mullerian hormone (AMH) polyclonal antibody (14461-1-AP, 1:5000, Proteintech, USA), phosphate and tensin homolog (PTEN) polyclonal antibody (10047-1-AP, 1:5000, Proteintech, USA), AMP-activated protein kinase (AMPK) polyclonal antibody (10929-2-AP, 1:5000, proteintech, Wuhan, China) and SIRT1 polyclonal antibody (A00018-1, 1:1000, Boster, Wuhan, China).

Techniques: Expressing, Western Blot, Control

SIRT1/NRF2/GPX4 pathway is involved in hippocampal ferroptosis in aged mice. (A) WB images and quantification analysis of SIRT1, NRF2 and GPX4 in the hippocampus of aged mice. (B) WB images and quantification analysis of SLC7A11, TFR1, IRP2 and ferritin in the hippocampus of aged mice ( n = 3 per group). (C) qRT‐PCR expression of SIRT1, NRF2, GPX4, SLC7A11, TFR1, IRP2 and ferritin mRNA in the hippocampus of aged mice ( n = 3 per group). Values are presented as mean ± SEM. ** p < 0.01 compared with the C group; # p < 0.05 and ## p < 0.01 compared with the M group; + p < 0.05 and ++ p < 0.01 and compared with the EX group.

Journal: Journal of Cellular and Molecular Medicine

Article Title: Electroacupuncture Pretreatment Ameliorates Perioperative Neurocognitive Disorder in Aged Mice by Inhibiting Ferroptosis Through the SIRT1 / NRF2 / GPX4 Pathway

doi: 10.1111/jcmm.71021

Figure Lengend Snippet: SIRT1/NRF2/GPX4 pathway is involved in hippocampal ferroptosis in aged mice. (A) WB images and quantification analysis of SIRT1, NRF2 and GPX4 in the hippocampus of aged mice. (B) WB images and quantification analysis of SLC7A11, TFR1, IRP2 and ferritin in the hippocampus of aged mice ( n = 3 per group). (C) qRT‐PCR expression of SIRT1, NRF2, GPX4, SLC7A11, TFR1, IRP2 and ferritin mRNA in the hippocampus of aged mice ( n = 3 per group). Values are presented as mean ± SEM. ** p < 0.01 compared with the C group; # p < 0.05 and ## p < 0.01 compared with the M group; + p < 0.05 and ++ p < 0.01 and compared with the EX group.

Article Snippet: The membrane was then incubated overnight at 4°C with primary antibodies: SIRT1 (1:850; Lot‐19G10A10; BOSTER), NRF2 (1:1500; Cat#YT3189; Immunoway), iron regulatory protein 2 (IRP2) (1:3000; Cat#YN3307; Immunoway), transferrin receptor 1 (TFR1) (1:750; LotNo‐23BP65E1; BOSTER), GPX4 (1:1500; Cat#YN3047; Immunoway), ferritin (1:3000; Cat#YT1692; Immunoway) and SLC7A11 (1:2000; Cat#YT8130; Immunoway).

Techniques: Quantitative RT-PCR, Expressing

EA ameliorates sevoflurane aesthesia‐induced ferroptosis in the hippocampus of aged mice through the SIRT1/NRF2/GPX4 signalling pathway. (A) Representative immunofluorescence staining of GPx4 (green) and NeuN (red) in the hippocampal CA1 region and fluorescence intensity of GPX4 levels in NeuN‐positive cells quantified in each group. Scale bar = 60 μm. (B) Representative TEM images of hippocampal neuron mitochondria in different groups. Scale bar = 2 μm. Values are presented as mean ± SEM ( n = 3 per group). **** p < 0.0001 compared with the C group; #### p < 0.0001 compared with the M group; ++++ p < 0.0001 compared with the EX group.

Journal: Journal of Cellular and Molecular Medicine

Article Title: Electroacupuncture Pretreatment Ameliorates Perioperative Neurocognitive Disorder in Aged Mice by Inhibiting Ferroptosis Through the SIRT1 / NRF2 / GPX4 Pathway

doi: 10.1111/jcmm.71021

Figure Lengend Snippet: EA ameliorates sevoflurane aesthesia‐induced ferroptosis in the hippocampus of aged mice through the SIRT1/NRF2/GPX4 signalling pathway. (A) Representative immunofluorescence staining of GPx4 (green) and NeuN (red) in the hippocampal CA1 region and fluorescence intensity of GPX4 levels in NeuN‐positive cells quantified in each group. Scale bar = 60 μm. (B) Representative TEM images of hippocampal neuron mitochondria in different groups. Scale bar = 2 μm. Values are presented as mean ± SEM ( n = 3 per group). **** p < 0.0001 compared with the C group; #### p < 0.0001 compared with the M group; ++++ p < 0.0001 compared with the EX group.

Article Snippet: The membrane was then incubated overnight at 4°C with primary antibodies: SIRT1 (1:850; Lot‐19G10A10; BOSTER), NRF2 (1:1500; Cat#YT3189; Immunoway), iron regulatory protein 2 (IRP2) (1:3000; Cat#YN3307; Immunoway), transferrin receptor 1 (TFR1) (1:750; LotNo‐23BP65E1; BOSTER), GPX4 (1:1500; Cat#YN3047; Immunoway), ferritin (1:3000; Cat#YT1692; Immunoway) and SLC7A11 (1:2000; Cat#YT8130; Immunoway).

Techniques: Immunofluorescence, Staining, Fluorescence